Current Research Projects

Ongoing Research Projects:

  • Establishment of Intra-brain Stem Xenograft Mouse Models and Permanent Cell Cultures of DIPG
  • An epidemiological study to determine incidence patterns of DIPG in North America
  • Patterns of cerebrospinal fluid diversion and survival in children with diffuse intrinsic pontine glioma
  • Comprehensive Molecular-Based Cross-Species Comparison of DIPG Biology
  • Radiogenomic Evaluation of Radiation Resistance in Diffuse Intrinsic Pontine Glioma
  • Characteristics of Diffuse Intrinsic Pontine Gliomas in Patients Over 10 Years Old: A DIPG Registry Study
  • Determining predictive factors of survival through clinicopathologic, genomic and radiographic analysis of infants < 3 years of age with Diffuse Intrinsic Pontine Glioma: A study from the International DIPG Registry
  • Diffuse Intrinsic Pontine Glioma (DIPG): the Australian Experience
  • Patterns of cerebrospinal fluid diversion and survival in children with diffuse intrinsic pontine glioma
  • Clinical, Radiological, Histological, and Molecular Characteristics of Patients with DIPG who Survive ≤ 3 months from Diagnosis Despite Therapy
  • Re-irradiation of children with DIPG: practices and outcomes
  • Characterizing temporal genomic heterogeneity in pediatric DIPG
  • Elucidating lipid metabolic reprogramming in Diffuse Intrinsic Pontine Glioma
  • STAT3 expression in patients with diffused intrinsic pontine glioma
  • Control group for: A safety run-in, phase 2 trial of Convection Enhanced Delivery (CED) of Carboplatin and Sodium Valproate into the pons for the treatment of Diffuse Intrinsic Pontine Glioma (DIPG) after radiotherapy in children aged 3-17 years
  • A systematic survey of non-coding somatic mutations in DIPG

Manuscripts Published:

To submit a research proposal please contact the Registry office.

Or access the application here.